Systematic review finds that vitamin D intake in early life may be associated with a reduced risk of type 1 diabetes

Cod liver oil

Vitamin D is suspected of having a role in the development of type 1 diabetes.  Previous studies have been small-scale and inconclusive. Now we have a systematic review of the observational evidence about the relationship between consumption of Vitamin D in early life (or during pregnancy) and the risk of developing type 1 diabetes later [read the full story…]

More evidence needed on the benefits of CGM in children with type 1 and adults with type 2

SMBG

Previous systematic reviews and meta-analyses have failed to turn up clear evidence on the benefits and harms of continuous glucose monitoring (CGM) in children with type 1 diabetes and insulin-using patients with type 2 diabetes. This systematic review set out to update this state of affairs in the light of recent studies. In children with [read the full story…]

Ethnicity, parenting, stress and self-efficacy are all associated with glycaemic control in young people with diabetes

Child with a megaphone

This review was motivated by the need to understand the barriers to achieving and maintaining good metabolic control among children and adolescents. From insulin pump (CSII) therapy to carbohydrate counting, technology has advanced rapidly since the Diabetes Control & Complications Trial.  However, this has not been matched with efforts to understand the impact of human [read the full story…]

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Review: children and adolescents with type 1 diabetes can have the same quality of life as those without it

A child tests her blood sugar

A new systematic review summarises a number of studies that examined how diabetes affects the quality of life of children and adolescents. Clinical question: In children with type 1 diabetes, is quality of life worse compared with the general population? The evidence: Is it not clear exactly how the reviewers calculated the “effect size” on [read the full story…]

Eating disorders are common and problematic in adolescents with type 1 diabetes.

eatingdisorder_scales

Young people with diabetes often struggle with diet in their teens.  A new systematic review looks at how common problems with eating are in adolescents with type 1 diabetes, in comparison with their non-diabetic peers. Clinical question: In young adults with type 1 diabetes, what is the prevalence of eating problems? The review differentiated between [read the full story…]

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Review: more evidence needed for metformin in children with type 2 diabetes

A child tests her blood sugar

Metformin is usually the first line of active treatment for type 2 diabetes in adults. However, like many drugs its safety and effectiveness has not be adequately studied in children.  With more children being diagnosed as type 2, should metformin also be the first port of call for them? Clinical question: In children and adolescents [read the full story…]

Review: insulin pumps may improve quality of life and glycaemic control in adults with type 1 diabetes

pump

What are the benefits of insulin pumps compared with multiple daily injections of insulin?  This report by the US Agency for Healthcare Quality and Research summarises what the evidence says. Clinical question: In diabetics using insulin, does continuous subcutaneous insulin infusion (CSII), compared with multiple daily injections (MDI), improve quality of life or glycaemic control? The [read the full story…]

Possible benefits of insulin pumps compared with multiple daily injections

Insulin Pump with sensor

An appraisal of a 2010 systematic review of continuous subcutaneous insulin infusion (CSII, or insulin pumps) has been published in DARE. Research question: In diabetes, does CSII as compared with multiple daily injections (MDI), improve the clinical or cost-effectiveness of care? The review included both adults and children with type 1 or type 2 diabetes.  [read the full story…]