ACE inhibitors significantly reduce the risk of diabetic kidney disease

Kidney

Kidney disease is one of the most serious complications of diabetes.  Reducing its incidence can greatly enhance survival, quality of life and reduce costs of care.  Keeping blood pressure under control is essential to this effort.  NICE guidance recommends ACE inhibitors as a first-line therapy for patients with diabetes and high blood pressure. However, a [read the full story…]

Eating disorders are common and problematic in adolescents with type 1 diabetes.

Young people with diabetes often struggle with diet in their teens.  A new systematic review looks at how common problems with eating are in adolescents with type 1 diabetes, in comparison with their non-diabetic peers. Clinical question: In young adults with type 1 diabetes, what is the prevalence of eating problems? The review differentiated between [read the full story…]

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New guidelines for the management of diabetic retinopathy

Retinopathy

The Canadian Ophthalmological Society has published new guidance for the management of diabetic retinopathy. The guideline provides explicit account of the methods used to identify and evaluate the evidence and arrive at consensus.  Recommendations for clinical practice are set apart from the text that describes the evidence. The guideline covers: Definitions of disease Epidemiologyof diabetes [read the full story…]

Canadian guidelines for managing diabetic retinopathy

Retinopathy

The Canadian Journal of Opthalmology has recently published guidelines for managing diabetic retinopathy by the Canadian Ophthalmological Society. Coverage: Methodology Definitions Epidemiology Screening Telehealth and Teleophthalmology Risk Factors For And Prevention Of Progression Of Diabetic Retinopathy Treatment Modalities Pregnancy Neovascularization of The Iris Economic Considerations Support Appraisal hints: Does this guidance conform to AGREE principles? [read the full story…]

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Increased risk of acute pancreatitis in people with diabetes

A pancreas

We already know that pancreatitis can lead to diabetes.  This systematic review of observational studies looked at whether people with diabetes can subsequently develop pancreatitis. Clinical question: In people with diabetes, what is the risk of developing acute pancreatitis? The reviewers were interested in studies that report new (incident) cases of pancreatitis rather than existing [read the full story…]

Metformin may reduce the risk of cancer, but more research is needed

This systematic review looked at the relationship between oral antidiabetic drugs and the risk of cancer. Clinical question: In type 2 diabetes, does treatment with metformin or sulphonylurea affect the risk of cancer? The evidence: The reviewers found 17 observational studies reporting 37,632 cases of cancer.  When they pooled the data from these studies they [read the full story…]

NHS Atlas of Variation in Diabetes in England

The NHS Atlas of Variation series is intended to support local decision making to increase the value which a population receives from the resources spent on their healthcare. The aim of the Diabetes Atlas is to identify and quantify the extent of ‘unwarranted’ variation that may be due to unjustified geographical differences in medical practice [read the full story…]

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Greater whole grain intake is associated with a lower risk of type 2 diabetes

Whole Grain

This systematic review set out to establish whether whole grains specifically contribute to a reduction in the risk of developing type 2 diabetes. Clinical question: In healthy indivduals, is consumption of whole grains associated with a reduced risk of type 2 diabetes. The reviewers were also interested in the effects on cardiovascular disease and weight. [read the full story…]

Sedentary behaviour is associated with metabolic syndrome

We already know that sedentary lifestyle is associated with a greater risk of type 2 diabetes.  This systematic review looked for an association with metabolic syndrome, a precursor condition of diabetes. Clinical question: Is a sedentary lifestyle associated with a high risk of developing metabolic syndrome? Metabolic syndrome is the presence of three of the [read the full story…]

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Coffee intake was associated with a lower incidence of type 2 diabetes

A new systematic review has summarised the findings of observational research into the association between coffee and type 2 diabetes. Clinical question: Is coffee intake associated with an increased risk of developing diabetes? The reviewers wanted to explore whether different amounts of coffee intake affected the risk differently. The evidence: The reviewers searched MEDLINE for [read the full story…]