No evidence for a dose-response effect for aspirin preventing cardiovascular events

This systematic review summarises the evidence for giving aspirin to all diabetic patients to prevent cardiovascular deaths at doses above 100 mg per day. Clinical question: In diabetes, does > 100mg/day aspirin prevent mortality? The reviewers stratified their analysis by dosage, and also looked at cardiovascular mortality, myocardial infarction and stroke. The evidence The reviewers [read the full story…]

In diabetes, aspirin may prevent major cardiovascular events

Red blood cells

Aspirin is widely used to prevent cardiovascular events in people with a history of cardiovascular disease (CVD). Many people believe that it may also prevent CVD in people who have no previous history of CVD, so-called “primary prevention”.  However, the evidence is unclear. As diabetes is an important risk factor for CVD, a systematic review [read the full story…]