Diabetes education is more effective if it’s culturally sensitive

Asian couple

Another one to file under “stating the obvious”, you might think. Sadly, it’s not that obvious, as many patients would attest. This is also evidenced by the recent randomised controlled trial (RCT) on giving diet and lifestyle advice to try to prevent diabetes.  The paper in the Lancet reported a reduction in body weight in [read the full story…]

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A diet containing low fat dairy may reduce the risk of type 2 diabetes

A cow

It has been suggested that dairy products might have a preventive effect against type 2 diabetes.  However, the results of observational studies looking at the correlation between the consumption of dairy and incidence of type 2 have been inconclusive. A new systematic review set out to combine the evidence from these different studies into an [read the full story…]

Systematic review finds that vitamin D intake in early life may be associated with a reduced risk of type 1 diabetes

Cod liver oil

Vitamin D is suspected of having a role in the development of type 1 diabetes.  Previous studies have been small-scale and inconclusive. Now we have a systematic review of the observational evidence about the relationship between consumption of Vitamin D in early life (or during pregnancy) and the risk of developing type 1 diabetes later [read the full story…]

More evidence needed for ADP-antagonists to prevent CVD in type 2 diabetes

ECG readout

This Cochrane systematic review looked at whether adenosine-diphosphate (ADP) receptor antagonists such as clopidogrel and ticlopidine,  can prevent cardiovascular disease (CVD) in type 2 diabetes mellitus. These drugs have been shown to reduce the risk of cardiovascular outcomes in non-diabetic patients.  However, few studies have looked at the diabetic population.  As people with type 2 [read the full story…]

Emerging evidence about the impact of different statins on the risk of diabetes

A pill

Recent evidence has shown that statins can increase the incidence of new-onset diabetes, leading to an official warning by the FDA.  This has huge implications for practice, as these drugs are widely used to reduce the risk of cardiovascular disease in patients with and without diabetes.  Selecting the right treatment and balancing the proven benefits [read the full story…]

ACE inhibitors significantly reduce the risk of diabetic kidney disease


Kidney disease is one of the most serious complications of diabetes.  Reducing its incidence can greatly enhance survival, quality of life and reduce costs of care.  Keeping blood pressure under control is essential to this effort.  NICE guidance recommends ACE inhibitors as a first-line therapy for patients with diabetes and high blood pressure. However, a [read the full story…]

Absence of evidence on whether exercise can prevent gestational diabetes

A pregnant woman

Research has shown that light to moderate exercise during pregnancy is beneficial for mother and baby alike.  It has also been shown to prevent type 2 diabetes in men and non-pregnant women.  This Cochrane review looked at whether it can prevent diabetes in pregnant women. Clinical question: In pregnant women, does exercise prevent gestational diabetes? [read the full story…]

New NICE guidance on preventing type 2 diabetes in high risk individuals

Photograph of a bowl of fruit

The National Institute for Health and Clinical Excellence (NICE) has just published important guidance for everyone who is involved identifying people at high risk of type 2 diabetes and in preventing or delaying its onset. This includes GPs, nurses and other health professionals, as well as commissioners and managers within the NHS, local authorities and [read the full story…]

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Greater whole grain intake is associated with a lower risk of type 2 diabetes

Whole Grain

This systematic review set out to establish whether whole grains specifically contribute to a reduction in the risk of developing type 2 diabetes. Clinical question: In healthy indivduals, is consumption of whole grains associated with a reduced risk of type 2 diabetes. The reviewers were also interested in the effects on cardiovascular disease and weight. [read the full story…]

TZDs may prevent type 2 diabetes

A colourful selection of pills

The Centre for Reviews and Dissemination (CRD) published an appraisal of a systematic review of drug interventions to prevent type 2 diabetes. Clinical question: In high risk patients do oral antidiabetic drugs prevent progression to type 2 diabetes? The scope included thiazolidinediones, biguanides, alpha-glucosidase inhibitors, sulphonylureas, glinides and dipeptidyl peptidase-4 inhibitors. The evidence: The reviewers [read the full story…]