In patients with type 1 diabetes, does Continuous glucose monitoring (CGM) compared with self-management of blood glucose (SMBG) lead to an improvement in glycaemic control or a reduction in hypoglycemia?
Systematic review of randomised trials. 14 trials were found, comprising 1,268 participants.
Real-time CGM was associated with a 0.26% (95% CI: -0.34% to -0.19%) greater mean reduction in HbA1c compared with SMBG. CGM patients had fewer hypoglycemic episodes.
Users of this research are advised to consider:
- Whether the reviewers identified all of the relevant studies
- Whether they carried out blind, independent evaluation of study quality and extraction of data
- Could the individual studies have been affected by significant bias?
- Whether the individual studies were sufficiently similar to merit combining into one overall estimate of benefit
- Was the observed benefit clinically significant and achievable in real life?
Wojciechowski P, Ryś P, Lipowska A, Gawęska M, Małecki MT. Efficacy and safety comparison of continuous glucose monitoring and self-monitoring of blood glucose in type 1 diabetes: systematic review and meta-analysis. Pol Arch Med Wewn. 2011 Oct;121(10):333-44.