This observational cohort study looked at whether having chronic kidney disease (CKD) predicts outcome of revascularisation of ulcerated feet in a cohort of patients undergoing treatment at a vascular surgery unit in Finland.
In people with diabetes and ulcerated foot, does CKD predict the outcome of surgical revascularisation?
The researchers collated data from a cohort of 597 patients who had 732 revascularisation procedures.
They found that people with more severe chronic kidney disease had a greater risk of amputation than people with less severe or no CKD. Other factors were also important, however, including the position and type of revascularisation procedure, pulmonary disease and gangrene.
Users of this research should consider:
- Whether enough participants were included in the study.
- How participants were selected and whether this was consecutive.
- Were the participants recruited at an equivalent stage of ulceration?
- Was everyone followed-up consistently?
- Were outcomes and CKD status adequately defined?
- The significance of other prognostic factors identified in this study and elsewhere.
Venermo M, Biancari F et al. The role of chronic kidney disease as a predictor of outcome after revascularisation of the ulcerated diabetic foot. Diabetologia. 2011 Dec;54(12):2971-7. Epub 2011 Aug 16.
Recent posts about diabetes complications, including foot ulcers, revascularisation and risk of amputation.