Managing high blood pressure should be a top priority in type 2 diabetes


This is a consensus statement from an expert review by the Canadian Hypertension Education Program and the Canadian Diabetes Association. The reviewers conducted a systematic search for randomised trials and systematic reviews about diabetes and hypertension.

They conclude that “reducing blood pressure pharmacologically is single-handedly the most effective way to reduce rates of death and disability in patients with diabetes, particularly associated cardiovascular risks.”  This can mean that combination treatments are needed to achieve good control of blood pressure

Furthermore, they note that the costs of additional treatment are outweighed by the consequences of not treating hypertension.

Appraisal hints

Readers of this paper should consider:

  • The quality of evidence in respect of the benefits associated with individual treatments, combination treatments and  cost-effectiveness analysis.
  • Applicability to individual patients.
  • Adverse effects of the possible treatments and combinations of treatments.


Hutchins V, Zhang B, Fleurence RL, Krishnarajah G, Graham J.  A systematic review of adherence, treatment satisfaction and costs, in fixed-dose combination regimens in type 2 diabetes. Can Fam Physician. 2011 Sep;57(9):997-1002.

The full text is available at the above link.

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I am an information scientist with an interest in making knowledge from systematic research more accessible to people who need it. This means you. I've been attempting this in the area of Evidence-Based Health Care since 1995. So far the results have been mixed. For some reason we expected busy clinicians to search databases and appraise papers instead of seeing patients. We also expected publishers to make the research freely available to the people who paid for it.. Ha! Hence The National Elf service.

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