This review collated data from over 80 studies of different insulin regimens to determine what proportion of people with type 2 diabetes patients achieve a glycosylated haemoglobin target of HbA1c of 7% or lower:
- Basal insulin: 37.2% (31.5-43.1%)
- Biphasic insulin: 35.3% (28.9-42.1%)
- Prandial insulin: 37.5% (27.7-47.9%)
- Basal-bolus insulin: 51.2% (41.4-61.1%)
Note that there may be many other factors at play here, such as a patient being assigned to a particular therapy because of poor control. The wide confidence intervals are also notable.
Users of this research are advised to consider:
- Possible sources of bias in the individual studies.
- The amount of uncertainty around the overall percentages quoted above.
- There were a lot of differences between the studies in terms of patients, interventions and outcomes.
- Whether the validity of the meta-analysis compromised by this heterogeneity.
You may be better to look for a good quality individual study that is more relevant to your circumstances.